| Active Ingredient | ASPIRIN | DIPYRIDAMOLE |
| Therapeutic Class | VASODILATING AGENTS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | BETAHISTINE |
| Therapeutic Class | VASODILATING AGENTS |
| Indications | Vertigo, tinnitus and hearing loss associated with Mé•nière'sdisease. |
| Caution | Gastro-intestinal disturbances; headache; pruritus; rashes. Betahistine should be given with care to patients with asthma, peptic ulcer disease or a history pepticulcer disease. |
| Dose Range | Initially 16mg 3 times a day, maintenance 24-48mg daily. Dose preferably taken with food. |
| Drug Interactions | |
| Pregnancy | Avoid unless clearly necessary. |
| Breast Feeding | Use only if potential benefit outweighs risk. |
| Active Ingredient | VASODILATING AGENTS |
| Therapeutic Class | VASODILATING AGENTS |
| Indications | |
| Caution | |
| Dose Range | |
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| Pregnancy | |
| Breast Feeding |
| Active Ingredient | GLYCERYL TRINITRATE |
| Therapeutic Class | NITRATES AND NITRITES |
| Indications | Used in treatment of angina at the onset of the attack, and in some cases for prophylaxis. |
| Caution | Over dosage:- palpitations, dizziness, blurred vision, headache, flushing followed by pallor. Postural hypotension, bradycardia, lightheadedness, reflux esophagus, contact dermatitis. |
| Dose Range |
Acute angina treatment: Sublingual Tablets (0.15 -0.6mg) or spray (0.4mg) may be repeated every 5 minutes until relief occurs; or 3 doses have been taken. To be taken under the tongue. Patients are tobe dispensed one full bottle of tablets every 2- |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ISOSORBIDE DINITRATE |
| Therapeutic Class | NITRATES AND NITRITES |
| Indications | Prophylaxis and treatment of angina. |
| Caution | Hypotension, dizziness, headache, peripheral edema and tolerance. |
| Dose Range |
Angina: Initially 20mg-120mg 2-3 times daily, to a maximum of 240mg/day. AcuteAngina: 2.5-10mg SL or 15 minutes before activity. CHF: 5-10mg SL every 2 hours or 60-160mg/day in divided doses to a maximum of 240mg/day . |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ISOSORBIDE MONONITRATE |
| Therapeutic Class | NITRATES AND NITRITES |
| Indications | Prophylaxis and long-term management of angina pectoris. |
| Caution | Postural hypotension, dizziness, syncope and vascular headache. Avoid alcohol. Take on an empty stomach with a full glass of water. |
| Dose Range | Regular release: 20mg 2-3 times a day .Sustained release: 30-60mg once daily up to a maximum of 120mg once daily in divided doses.. The 60mg extended release may be broken but not chewed or crushed. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | NITROGLYCERINE |
| Therapeutic Class | NITRATES AND NITRITES |
| Indications | |
| Caution | |
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| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | SILDENAFIL |
| Therapeutic Class | PHOSPHODIESTERASE INHIBITORS |
| Indications | Pulmonary hypertension. |
| Caution | Hypotension. Headache, flushing, dyspepsia, oedema, bronchitis, cough, GI disturbances, Priapism can occur. |
| Dose Range | Adult: 5 or 20mg three times daily given 4-6 hours apart. |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | ALPROSTADIL |
| Therapeutic Class | VASODILATING AGENTS, MISCELLANEOUS |
| Indications | Congenital heart disease in neonates until surgery is possible. |
| Caution | Infants: apnoea, fever, flushing, hypotension, bradycardia, tachycardia, diarrhoea, and convulsions. |
| Dose Range | Pediatric: Continuous intravenous infusion, initially 5 nanograms /kg/ minute, adjusted according to response, adjusted in steps of 5 nanograms/ kg / minute ( max . Per dose 100 nanograms /kg/minute), |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | PAPAVERINE |
| Therapeutic Class | VASODILATING AGENTS, MISCELLANEOUS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |