Displaying 1 - 3 of 3
| Active Ingredient | ALTEPLASE |
| Therapeutic Class | THROMBOLYTIC AGENTS |
| Indications | Intravenous alteplase is effective in producing recanalization of occluded coronary arteries following acute my ocardial infarction. Also effective in the treatment of acute massive pulmonary emboli More ... |
| Caution | Bleeding complications, reperfusion arrhythmias and reinfarction are the primary concerns of therapy . |
| Dose Range | The recommended dose to produce recanalization following my ocardial infarction is 100mg given as a “front -loaded” infusion. |
| Drug Interactions | |
| Pregnancy | Alteplase should be used during pregnancy only when clearly needed. There is a r More ... |
| Breast Feeding |
| Active Ingredient | STREPTOKINASE |
| Therapeutic Class | THROMBOLYTIC AGENTS |
| Indications | Thromboembolic disorders. |
| Caution |
Haemorrhage, allergic reactions, rare- Guillain-Barre syndrome. Due to risk of anaphylaxis, repeated use is contraindicated. |
| Dose Range | 1.5 million units infused over 1 hour as soon as possible after the onset of symptoms. Pulmonary embolism and other arteriovenous occlusions: an initial loading dose of 250 000 units infused intravenously over 30 minutesfollowed by a maintenance dos |
| Drug Interactions | |
| Pregnancy | Avoid use during pregnancy. |
| Breast Feeding |
| Active Ingredient | TENECTEPLASE |
| Therapeutic Class | THROMBOLYTIC AGENTS |
| Indications | As for streptokinase. |
| Caution | As for streptokinase. |
| Dose Range | Adult: Dose is based on body -weight and ranges from 30 mg in patients less than 60 kg to a maximum of 50 mg in those 90 kg or above. |
| Drug Interactions | |
| Pregnancy | Avoid use during pregnancy. |
| Breast Feeding |