| Active Ingredient | APIXABAN |
| Therapeutic Class | DIRECT THROMBIN INHIBITORS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | DABIGATRAN |
| Therapeutic Class | DIRECT THROMBIN INHIBITORS |
| Indications | Dabigatran is a direct thrombin inhibitor. It is used for the prophylaxis of venous thromboembolism in patients undergoing orthopaedic surgery and the prevention of stroke and systemic embolisation in More ... |
| Caution | Dabigatran should not be used in patients who are at a high risk for bleeding. It is contraindicated for those patients who have mechanical prosthetic heart valves because of thromboembolism and major More ... |
| Dose Range | Prophylaxis of venous embolism after orthropaedic surgery: Adult: 18-74 years, 110mg to be taken 1-4 hours after surgery, followed by 220mg once daily for 9 days , to be taken 12-24 hours after initial dose. Adult: 75years and older 110mg to be taken afte |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | RIVAROXABAN |
| Therapeutic Class | DIRECT THROMBIN INHIBITORS |
| Indications | |
| Caution | |
| Dose Range | |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |
| Active Ingredient | DALTEPARIN |
| Therapeutic Class | HEPARINS |
| Indications | Prophylaxis of ischemic complications and deep vein thrombosis. |
| Caution | See Heparin Sodium. |
| Dose Range |
Thromboprophylaxis in abdominal surgery: 2500-5000 iu s.c. 1-2 hours before surgery then once daily for 5-10 day s after surgery . Unstable Angina: 120 iu/kg to a maximum of 10,000 iu s.c. every 12 hours given with 75-165mg Asp irin daily for 5-8 |
| Drug Interactions | |
| Pregnancy | Not known to be harmful, low molecular weight heparins do not cross the placenta More ... |
| Breast Feeding | Dalteparin is distributed in breastmilk and should be used with caution in lacta More ... |
| Active Ingredient | ENOXAPARIN |
| Therapeutic Class | HEPARINS |
| Indications | Prevention of DVT in orthopedic, abdominal and gynaecologic surgical procedures. May also be used in DVT and pulmonary embolism. |
| Caution | See Heparin. Monitor patients for spinal/epidural bleeding. Nausea, fever, allergic reactions |
| Dose Range | Unstable Angina: 1mg/kg s.c. every 12 hours for 2-12 day s in conjunction with aspirin therap y (100-325mg once a day ) DVT Prophylaxis: 20-40mg s.c. 2 hours p rior to surgery and then every 24 hours or 30mg every 12 hours for 7-1 |
| Drug Interactions | |
| Pregnancy | Pregnancy itself increases the risk of thromboembolism. Pregnant women with a hi More ... |
| Breast Feeding | If enoxaparin therapy is required in nursing women, use of a preservative (benzy More ... |
| Active Ingredient | HEPARIN |
| Therapeutic Class | HEPARINS |
| Indications | Used to prevent thrombus formation or the extension of existing thrombus. |
| Caution | Exercise caution in the elderly and patients with history of pepticulcer. Since heparin is derived from animal tissue use with caution in patients with history of asthma, or allergy. Haemorrhage, More ... |
| Dose Range | DVT: i.v. 5000 units loading dose followed by 18 units/kg/hr given continuously adjusted according to resp onse. Postoperative venous thromboembolism: s.c. 5000 units 2 hours before surgery followed by 5000 units every 8-12 hours for 7 day s or until p |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding | If heparin therapy is required in nursing women, use of a preservative (benzyl a More ... |