| Active Ingredient | SACUBITRIL | VALSARTAN |
| Therapeutic Class | ANGIOTENSIN II RECEPTOR ANTAGONIST |
| Indications | Sacubitril and valsartan in fixed combination is used to reduce the risk of cardiovascular death and hospitalization for patients with chronic heart failure (New York Heart Association [NYHA] class 11 More ... |
| Caution | A history of angioedema with an ACE inhibitor or angiotensin 11receptor antagonist. Concomitant use with ACE inhibitors. Sacubitril/valsartan should not be administered within 36 hours of switching f More ... |
| Dose Range | Adult: The recommended initial dose of sacubitril /valsartan in patients with CHF who are stabilised on an ACE or ARB is sacubitril 49mg /valsartan 51 mg twice daily. 36 hours should have relapsed before starting sacubitril/valsartan, if patient was on a |
| Drug Interactions | |
| Pregnancy | |
| Breast Feeding |