Therapeutic Classifcation Notes (MISCELLANEOUS G. I. DRUGS)

MISCELLANEOUS G. I. DRUGS
H. Pylori Treatment In the treatment of H. pylori no one regimen can be considered definitive and consideration includes cost, compliance, side-effects, and efficacy. Patients unable to tolerate metronidazole would be better served by the 10-14 days regimen including Ampicillin. Please note that these regimens should be used with proven diagnosis of H. Pylori. 1. 10 - 14 Day Regimen • Proton Pump Inhibitor - twice daily dosing • Ampicillin 1g - twice daily dosing • Clarithromycin 500mg - twice daily dosing 2. 10 Day Regimen (for patients resistant to penicillin) • Proton Pump inhibitor - twice daily dosing • Metronidazole 400mg - twice daily dosing • Clarithromycin 250mg ◦ twice daily dosing • Pepto bismol 2 tbsp four times daily (help to over-come the metronidazole resistance)