Rx Name [CILASTATIN|IMIPENEM, 08120708]
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PRIMAXIN 500MG INJ (MSD/STO) IMIPENEM/CILASTA
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08120708
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CARBAPENEMS
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Aerobic and anaerobic Gram-positive and Gram-negative infections;
(not indicated for CNS infections) hospital-acquired septicaemia. |
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Diarrhoea; eosinophilia; nausea (may reduce rate of infusion); rash;
vomiting |
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Adult: 500mg every 6 hours, alternatively 1g every 8 hours.
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Manufacturer advises avoid unless potential benefit outweighs risk. Both imipenem and cilastatin sodium cross the placenta and are distributed into cord blood and amniotic fluid in humans.
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Present in milk but unlikely to be absorbed.
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