Displaying 81 - 100 of 199

Drugs to be avoided or used with caution in liver disease

Active Ingredient Comments
Haloperidol see Antipsychotics
Heparin Reduce dose in severe disease
Hydrochlorothiazide see Thiazides
Hydroxyprogesterone Hexanoate see Progestogens
Hydroxyzine see Antihistamines
Hypnotics see Anxiolytics and Hypnotics
Ibuprofen see NSAIDs
Imipramine see Antidepressants Tricylic
Indapamide see Thiazides
Indomethacin see NSAIDs
Isoniazid Avoid if possible idiosyncratic hepatoxicity more common
Isotretinoin Avoid - further impairment of liver function may occur
Isradipine Reduce dose
Itraconazole Avoid - toxicity with related drugs
Ketoconazole Induces hepatitis- like reaction; may accumulate in severe liver disease; contra-indicated unless no alternative
Ketoprofen see NSAIDs
Ketotifen see Antihistamines
Lignocaine Avoid (or reduce dose) in severe liver disease
Labetalol Avoid
Loop Diuretics Hypokalaemia may precipitate coma; potas-sium-sparing diuretic should be used to prevent this in-creased risk of hypomagnesae-mia in alcoholic cirrhosis