Formulary Monographs [GRISEOFULVIN, 081492]
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GRISEOFULVIN
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ANTIFUNGALS, MISCELLANEOUS
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Severe tinea infections. Not effective against candida albicans.
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Headache, gastrointestinal upset, rash, dry mouth, photosensitivity. Affects warfarin metabolism. Avoid in pregnancy, liver failure.
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Adult: 500mg-1g daily as a single dose or in divided doses (1g is for difficult to treat fungal infections) after meals for 30 days or more. Pediatric: 5-10mg/kg daily in 2 divided doses or as a single dose after meals. The oral suspension is reserved f
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Griseofulvin studies have shown the drug to be embryotoxic and/or teratogenic in animals. Griseofulvin may therefore cause fetal toxicity when administered to pregnant women.
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Avoid use unless potential benefit outweighs risk.
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