Formulary Monographs [BLEOMYCIN SULPHATE, 1000]

BLEOMYCIN SULPHATE
ANTINEOPLASTICS
Squamous cell carcinomas.
Extravasation, thromboembolism, nausea, vomiting,stomatitis, fever and chills, alopecia, pulmonary fibrosis.
i.v. i.m: 15 000 IU.3 times a week, or 30 000 IU. Twice a week in
combination regimens. This may be repeated, at 3 to 4 weeks intervals, up to a total cumulative dose of 500 000 IU. Dose and total cumulative dose should be reduced in those ov
Bleomycin sulfate can cause fetal toxicity when administered to pregnant women. Avoid during pregnancy.
Discontinue breastfeeding.